Site-specific range uncertainties caused by dose calculation algorithms for proton therapy
نویسندگان
چکیده
منابع مشابه
Site-specific range uncertainties caused by dose calculation algorithms for proton therapy.
The purpose of this study was to assess the possibility of introducing site-specific range margins to replace current generic margins in proton therapy. Further, the goal was to study the potential of reducing margins with current analytical dose calculations methods. For this purpose we investigate the impact of complex patient geometries on the capability of analytical dose calculation algori...
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PURPOSE Intensity modulated proton therapy (IMPT) is sensitive to errors, mainly due to high stopping power dependency and steep beam dose gradients. Conventional margins are often insufficient to ensure robustness of treatment plans. In this article, a method is developed that takes the uncertainties into account during the plan optimization. METHODS Dose contributions for a number of range ...
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The highly conformal dose distributions produced by scanned proton pencil beams (PBs) are more sensitive to motion and anatomical changes than those produced by conventional radiotherapy. The ability to calculate the dose in real-time as it is being delivered would enable, for example, online dose monitoring, and is therefore highly desirable. We have previously described an implementation of a...
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Introduction: The main advantage of using ion beams over photons in radiotherapy is due to their inverse depth-dose profiles, allowing higher doses to tumors, while better sparing normal tissues. When calculating dose distributions with ion beams, one crucial point is the uncertainty of the Bragg-peak range. Recently great effort is devoted to enhance the accuracy of the comput...
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ژورنال
عنوان ژورنال: Physics in Medicine and Biology
سال: 2014
ISSN: 0031-9155,1361-6560
DOI: 10.1088/0031-9155/59/15/4007